Pharma & Healthcare

The sustainable products hydrogen peroxide and peracetic acid are perfectly suited for effective cleaning and disinfection in hospitals, medical offices, and laundries, as well as industrial, institutional, and residential cleaning applications.

Hydrogen peroxide and peracetic acid are applied in the pharmaceutical and healthcare industries for dental disinfection and wound care, decontamination of surgical instruments as well as treatment of contact lenses. Our peroxides are ideally suited for the sanitization of devices for medical care to manage microbiological risks.

To cover an increased demand for products related to biocompatibility, hypoallergenic aspects, bio durability, flexibility and bacterial-resistance.

We offer highly pure natural and non-natural amino acids, salts and derivatives under the REXIM® and REXIVA® brands. These can be used for pharmaceutical applications, infant nutrition, clinical nutrition, medical nutrition, and food applications and as excipients. In addition to amino acids like L-Lysine, L-Methionine, L-Ornithine-L-Aspartate and many others, Evonik offers a broad range of corresponding services.

Our drug delivery technology EUDRATEC® ADD prevents dose dumping in oral dosage forms like multiparticulates and tablets. This can reduce the risk of unexpected API release even in instances of excessive alcohol intake.

To optimize the safety, performance and biocompatibility of medical devices, we offer an extensive portfolio of application services for bioresorbable polymers. We support you during each stage of the medical device design, product development, scale-up process, process optimization, prototyping, 3D printing process, analytics and medical device production.

Our RESOMER® biodegradable polymers made of polylactide (PLA), polycaprolactone (PCL) and polydioxanone improve the safety, biocompatibility and functional performance of medical devices and implants for orthopedic (e.g. interference screws, suture anchors, fracture plates), spine, dental (e.g membranes), cardiovascular (e.g. vascular closures or stents) and wound healing applications (e.g. sutures or ligating clips).

Since most APIs are produced by complex multi-step syntheses, selectivity is the major challenge, and an optimized yield in each step is essential for the economic viability of any synthetic route. We support both research-focused pharmaceutical originators and Contract Manufacturing Organizations (CMOs) by providing and developing standard and tailor-made catalysts.

Highly pure cGMP cell culture ingredients like amino acids, keto acids, lipids, carbohydrates and peptides out of Evonik’s cQrex® brand help to overcome solubility and stability issues related to glutamine, cysteine and tyrosine.

As one of the world’s leading CDMOs for complex parenteral drug products in the pharmaceutical industry, we offer pharma contract manufacturing services and solutions to add value at any product development stage including feasibility studies, excipient selection and supply, formulation development, process development and scale-up, clinical supply, QbD process characterization, GMP manufacturing and aseptic filling.

We are a contract manufacturing organization (CMO) for custom APIs, highly potent APIs (HPAPI) and intermediates. With our extensive exclusive synthesis capabilities, we are a preferred CMO/CDMO for chiral chemistry, flow chemistry, and continuous processing. We also support customers worldwide with microbial fermentation projects.

Chematic® detergents have been specially formulated for cleaning pharmaceutical production equipment after processing EUDRAGIT® film coating polymers. These cleaning agents developed by Dober reduce production and manufacturing downtimes of tablet coating equipment like drum coating and fluid bed coating machines.

Our advanced functional coating EUDRAGUARD® for nutraceutical solutions protects sensitive health ingredients and ensures the targeted release of active ingredients. We also provide ready-to-fill, functional capsules GuardCap™ which are coated with an EUDRAGUARD® biotic-based formulation. GuardCap™ can hold a range of fillings and are suitable for colonic delivery of nutraceuticals.

EUDRAGIT® controlled release polymers are the gold standard for film coating of tablets, capsules, multi-particulates, and other oral solid dosage forms. They act as enteric coatings for delayed release applications, protective and immediate release coatings, and for taste masking of bitter APIs. EUDRAGIT® can be used for solubility and bioavailability enhancement, 3D printing or microbiome delivery.

Our oral drug delivery technologies EUDRATEC® Fasteric and DuoCoat® enable rapid enteric drug release for precise targeting of the proximal region of the small intestine and the ileocolonic region. Both film coating technologies can be used across a range of dosage forms including multiparticulates, tablets and capsules.

Evonik offers a wide range of pre-formulation services including feasibility studies and proprietary systems. These support pharmaceutical, biotechnology and nutraceutical companies in the development and manufacturing of oral solid dosage forms that are ready for human clinical trials.

Our formulation development experts support pharmaceutical and biotechnology companies worldwide with complex oral dosage forms including small molecules, peptides, enzymes, nucleic acids, high potency APIs and controlled substances. We specialize in formulation for personalized medicine, 3D printing, pediatric or geriatric medicines, oncological, orphan and poorly soluble drugs, continuous manufacturing, microbiome delivery, and the oral administration of biologics.

Our range of EUDRAGIT® film coating polymers and our oral drug delivery technology EUDRATEC® COL for colon targeting can both be used for microbiota therapies and other microbiome-based products.

We are a supplier of high-quality generic active pharmaceutical ingredients (API), biocides and intermediates, including keto acids, amino acids, chlorhexidine and controlled substance APIs produced at trusted Western European cGMP facilities. Our intermediates include amino acids and derivatives being used as starting materials for APIs, as well as multiple types of phosphonium salts and boronic acids.

Our portfolio of health ingredients have proven scientific benefits and boost the performance, stability and bioavailability of dietary supplements and functional foods. Advanced health ingredients such as the highest load omega-3 powder AvailOm® , our high-load anthocyanin ingredient Healthberry® and our highly pure amino acids are part of our health ingredients portfolio.

Our LIPEX® liposome extruder is your pharmaceutical equipment of choice for seamless scale-up from research to commercial manufacturing. LIPEX® sets the industry standard for liposomal drug product manufacturing across the pharmaceutical and biotechnology industry. We are specialized in a range of equipment used in the drug product development of liposomes, polymeric microparticles, nanoparticles and implants.

We are a global microbial fermentation leader with over 30 years’ experience supporting customers from strain development to process optimization and large-scale manufacturing. Our global network of sites supports pharmaceutical and food companies with microbial fermentation for small and complex molecules as well as whole organisms and whole cell catalysts. 

Our solutions for mRNA and gene delivery build on our superior knowledge and experience of lipids and lipid nanoparticles (LNPs). As a CDMO leader we are your partner for high-quality GMP lipids. We also provide plant-derived cholesterol PhytoChol® and support clients with custom lipids from process development through process commercial manufacturing with non-GMP and GMP capabilities.

Safe, sustainable, natural and commercially scalable: – we offer two biomaterial solutions – our collagen platform and biosynthetic cellulose. VECOLLAN® is our recombinant collagen and provides medical, pharmaceutical, cell culture and tissue engineering innovators with a highly soluble and pure form of collagen. Our biosynthetic cellulose is ideally suited to medical applications such as wound dressings, implant materials and scaffolds for tissue engineering.

Our parenteral drug delivery solutions include our RESOMER® and LACTEL® portfolio of functional excipients for parenteral controlled release. We offer a versatile range of high-quality standard, custom and specialized biodegradable polymers for more safety, biocompatibility and supply security.

Petrochemicals specialties for the healthcare industry: Our solvents have been developed and tested for properties that are specifically required for medical and pharmaceutical applications.

How do you heat seal a blister packaging? By adding one pass direct heat seal adhesive laquer on the blister card. Our DEGACRYL® HS methacrylates blinders enable sustainable blister pharmaceutical packaging.

EUDRACAP®, our brand for enteric coated, ready-to-fill, pre-locked HPMC capsules, is suitable for drug fillings like powders, pellets and granules. It can be used for GI-targeting and other drug release profiles, solubility enhancement and microbiome delivery.

To ensure that high-speed systems for the production of tablets and pharmaceutical capsules run smoothly, the starting materials must exhibit optimum flow behavior. Silica as free flow agent ensure a uniform pharmaceutical active ingredient content in each tablet or capsule and increase production throughput.

Our EUDRAGIT® film coating polymers enhance drug solubility and bioavailability of oral dosage forms like tablets and capsules. These can be processed with hot melt extrusion (HME), top-spray granulation and spray drying. Our oral drug delivery technology EUDRATEC® SoluFlow turns poorly soluble drugs into free-flowing amorphous solid dispersions (ASD) to overcome poor drug solubility.

Endexo® is a proven surface modification technology based on low molecular weight fluorooligomers. Our technology enhances the biocompatibility of medical devices that come in contact with blood, tissue, or other biological fluids. Endexo® is a highly versatile platform for surface modification  and can be tailored to be compatible with a broad range of base polymers and manufacturing techniques.